Systems biology research requires access to sophisticated and expensive technologies. To develop, update and maintain such a technology infrastructure, CSBi is developing technology collaborations with companies across a range of industries that provide instruments and devices, reagents, computer hardware and software. The goals of such collaborations are joint technology development and applications enabled through the CSBi Technology Platform. For example, IBM is working with CSBi to build a grid-based IT infrastructure to support systems biology research, and to develop tools to deal with computationally intensive biological problems and highly unstructured data (i.e. imaging data).