Jeff Gore, Ph. D
MIT Department of Physics
B.S. Physics, mathematics, electrical engineering & economics, MIT, 1999
Ph.D. Physics, UC Berkeley, 2005
Pappalardo Postdoctoral Fellow, MIT Physics, 2006 – 2009
Assistant Professor, MIT Physics, Jan 2010 –
The Gore Lab uses microbes such as yeast and bacteria to experimentally probe fundamental theories in evolutionary dynamics, systems biology, and quantitative ecology.
As a Pappalardo Postdoctoral Fellow working together with Alexander van Oudenaarden, Jeff used sucrose metabolism in yeast as a model system to study the evolution of cooperation. The conditions required for the initiation and maintenance of cooperative behaviors is a classic problem in evolutionary biology. How can cooperators survive when they can be taken advantage of by "cheaters"? In the case of sucrose metabolism, Jeff found that cooperators can survive even in the presence of cheaters because the cooperators capture a small fraction (~1%) of the sugar they create before it is shared, thus making the interaction what game theorists call a snowdrift game.
- Snowdrift game dynamics and facultative cheating in yeast,
Jeff Gore, Hyun Youk, and Alexander van Oudenaarden,
Nature 459, 253 - 256 (2009).
- The yin and yang of nature [News & Views],
Jeff Gore and Alexander van Oudenaarden,
Nature 457, 271 - 272 (2009).
- DNA overwinds when stretched,
Jeff Gore, Zev Bryant, Marcelo Nollmann, Mai U. Le, Nicholas R. Cozzarelli, and Carlos Bustamante,
Nature 442, 836 - 839 (2006)
- Mechanochemical analysis of DNA gyrase using rotor bead tracking,
Jeff Gore, Zev Bryant, Michael D. Stone, Marcelo Nollmann, Nicholas R. Cozzarelli, and Carlos Bustamante,
Nature 439, 100 - 104 (2006).
- Structural transitions and elasticity from torque measurements on DNA,
Zev Bryant, Michael D. Stone, Jeff Gore, Steven B. Smith, Nicholas R. Cozzarelli, Carlos Bustamante,
Nature 424, 338 (2003).
Last Updated: July 23, 2009